Catestatin Regulates Epithelial Cell Dynamics to Improve Intestinal Inflammation

Catestatin Regulates Epithelial Cell Dynamics to Improve Intestinal Inflammation

Ulcerative colitis (UC) is characterized by aberrant regulation of tight junctions (TJ), signal transducer and activator of transcription 3 (STAT3), and interleukin (IL)-8/18, which lead to intestinal barrier defects. Catestatin (CST), an enterochromaffin-derived peptide, regulates immune communicat...

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Bibliographic Details
Main Authors: Nour Eissa, Hayam Hussein, Ruth Mesgna, Sandra Bonin, Geoffrey N. Hendy, Marie-Hélène Metz-Boutigue, Charles N. Bernstein, Jean-Eric Ghia
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Vaccines
Subjects:
chromogranin-A
colitis
host-defense peptides
inflammatory bowel diseases
innate immunity
intestinal permeability
mucosal drug action
Online Access:http://www.mdpi.com/2076-393X/6/4/67

Internet

http://www.mdpi.com/2076-393X/6/4/67

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