Ma Xing Shi Gan Decoction Attenuates PM2.5 Induced Lung Injury via Inhibiting HMGB1/TLR4/NFκB Signal Pathway in Rat

Ma Xing Shi Gan Decoction Attenuates PM2.5 Induced Lung Injury via Inhibiting HMGB1/TLR4/NFκB Signal Pathway in Rat

Ma Xing Shi Gan Decoction (MXD), a classical traditional Chinese medicine prescription, is widely used for the treatment of upper respiratory tract infection. However, the effect of MXD against particulate matters with diameter of less than 2.5 μm (PM2.5) induced lung injury remains to be elucidated...

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Bibliographic Details
Main Authors: Yu-xiang Fei, Bo Zhao, Qi-yang Yin, Yan-ying Qiu, Guang-hui Ren, Bo-wen Wang, Ye-fang Wang, Wei-rong Fang, Yun-man Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Pharmacology
Subjects:
Ma Xing Shi Gan Decoction
PM2.5
lung injury
macrophage
inflammatory reaction
HMGB1/TLR4/NFκB pathway
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01361/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.01361/full

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