PACE4-Based Molecular Targeting of Prostate Cancer Using an Engineered 64Cu-Radiolabeled Peptide Inhibitor

The potential of PACE4 as a pharmacological target in prostate cancer has been demonstrated as this proprotein convertase is strongly overexpressed in human prostate cancer tissues and its inhibition, using molecular or pharmacological approaches, results in reduced cell proliferation and tumor pro...

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Bibliographic Details
Main Authors: Frédéric Couture, Christine Levesque, Véronique Dumulon-Perreault, Samia Ait-Mohand, François D’Anjou, Robert Day, Brigitte Guérin
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558614001043