Omics-Based Approach Reveals Complement-Mediated Inflammation in Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS)

Omics-Based Approach Reveals Complement-Mediated Inflammation in Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS)

ObjectiveChronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a rare syndrome with relapsing brainstem/cerebellar symptoms. To examine the pathogenic processes and investigate potential biomarkers, we analyzed combined materials of brain and cer...

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Bibliographic Details
Main Authors: Morten Blaabjerg, Anne Louise Hemdrup, Lylia Drici, Klemens Ruprecht, Peter Garred, Romana Höftberger, Bjarne W. Kristensen, Daniel Kondziella, Tobias Sejbaek, Soren W. Hansen, Helle H. Nielsen, Pia Jensen, Morten Meyer, Friedemann Paul, Hans Lassmann, Martin R. Larsen, Zsolt Illes
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
CLIPPERS
proteomics
complement
cerebrospinal fluid
VCAM-1
ICAM-1
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00741/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00741/full

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