Targeting autophagy enhances heat stress-induced apoptosis via the ATP-AMPK-mTOR axis for hepatocellular carcinoma

Targeting autophagy enhances heat stress-induced apoptosis via the ATP-AMPK-mTOR axis for hepatocellular carcinoma

Purpose: Radiofrequency ablation (RFA) is widely accepted as a curative treatment for small hepatocellular carcinoma (HCC). However, insufficient RFA (IRFA) can lead to rapid local recurrence. The underlying mechanisms remain poorly understood. This study aimed to elucidate the role and regulatory m...

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Bibliographic Details
Main Authors: Jiayun Jiang, Shihan Chen, Kun Li, Chang Zhang, Yunhua Tan, Qingsong Deng, Yuelong Chai, Xiaofei Wang, Geng Chen, Kai Feng, Leida Zhang, Chuan-Ming Xie, Kuansheng Ma
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:International Journal of Hyperthermia
Subjects:
hepatocellular carcinoma
radiofrequency ablation
ampk
autophagy
apoptosis
Online Access:http://dx.doi.org/10.1080/02656736.2019.1600052

Internet

http://dx.doi.org/10.1080/02656736.2019.1600052

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