Validation of two multiplex platforms to quantify circulating markers of inflammation and endothelial injury in severe infection.

Biomarkers can prognosticate outcome and enable risk-stratification. In severe infection, focusing on multiple markers reflecting pathophysiological mechanisms of organ injury could enhance management and pathway-directed therapeutics. Limited data exist on the performance of multiplex biomarker pla...

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Bibliographic Details
Main Authors: Aleksandra Leligdowicz, Andrea L Conroy, Michael Hawkes, Kathleen Zhong, Gerald Lebovic, Michael A Matthay, Kevin C Kain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5395141?pdf=render