A Dynamic Bayesian Network model for the simulation of Amyotrophic Lateral Sclerosis progression
Abstract Background Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease progressively affecting upper and lower motor neurons in the brain and spinal cord. Mean life expectancy is three to five years, with paralysis of muscles, respiratory failure and loss of vital functi...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-04-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-019-2692-x |