The Role of SNP Interactions When Determining Independence of Novel Signals in Genetic Association Studies—An Application to <i>ARG1</i> and Bronchodilator Response

The Role of SNP Interactions When Determining Independence of Novel Signals in Genetic Association Studies—An Application to <i>ARG1</i> and Bronchodilator Response

Genome-wide association studies (GWAS) play a critical role in identifying many loci for common diseases and traits. There has been a rapid increase in the number of GWAS over the past decade. As additional GWAS are being conducted, it is unclear whether a novel signal associated with the trait of i...

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Bibliographic Details
Main Authors: Ryan Walsh, Kirsten Voorhies, Merry-Lynn McDonald, Michael McGeachie, Joanne E. Sordillo, Christoph Lange, Ann Chen Wu, Sharon M. Lutz
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Journal of Personalized Medicine
Subjects:
epistasis
SNP by SNP interactions
independence
GWAS
<i>ARG1</i>
bronchodilator response
Online Access:https://www.mdpi.com/2075-4426/11/2/145

Internet

https://www.mdpi.com/2075-4426/11/2/145

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