Isoniazid metabolism and hepatotoxicity

Isoniazid (INH) is highly effective for the management of tuberculosis. However, it can cause liver injury and even liver failure. INH metabolism has been thought to be associated with INH-induced liver injury. This review summarized the metabolic pathways of INH and discussed their associations wit...

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Bibliographic Details
Main Authors: Pengcheng Wang, Komal Pradhan, Xiao-bo Zhong, Xiaochao Ma
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383516301277