Molecular Aspects of Adipose-Derived Stromal Cell Senescence in a Long-Term Culture: A Potential Role of Inflammatory Pathways

Long-term culture of mesenchymal stromal/stem cells in vitro leads to their senescence. It is very important to define the maximal passage to which the mesenchymal stromal/stem cells maintain their regenerative properties and can be used for cellular therapies and construction of neo-organs for clin...

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Bibliographic Details
Main Authors: Marta Pokrywczynska, Małgorzata Maj, Tomasz Kloskowski, Monika Buhl, Daria Balcerczyk, Arkadiusz Jundziłł, Kamil Szeliski, Marta Rasmus, Tomasz Drewa
Format: Article
Language:English
Published: SAGE Publishing 2020-04-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689720917341