A potent endocytosis inhibitor Ikarugamycin up-regulates TNF production

A potent endocytosis inhibitor Ikarugamycin up-regulates TNF production

Ikarugamycin (IK) is an antibiotic which has been reported to have a variety of functions, such as inhibition of clathrin-mediated endocytosis (CME), anti-tumor effects and regulation of the immune system. Whether IK influences cytokine production is poorly understood. We have investigated the relat...

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Bibliographic Details
Main Authors: Ai Minamidate, Michio Onizawa, Chikako Saito, Rie Hikichi, Tomoaki Mochimaru, Mai Murakami, Chiharu Sakuma, Takehito Asakawa, Yuichi Hiraoka, Shigeru Oshima, Takashi Nagaishi, Kiichiro Tsuchiya, Hiromasa Ohira, Ryuichi Okamoto, Mamoru Watanabe
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
Inflammation
TNF
Ikarugamycin
Endocytosis
Online Access:http://www.sciencedirect.com/science/article/pii/S240558082100159X

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http://www.sciencedirect.com/science/article/pii/S240558082100159X

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