CD47 surface stability is sensitive to actin disruption prior to inclusion within the band 3 macrocomplex

Abstract CD47 is an important ‘marker of self’ protein with multiple isoforms produced though alternative splicing that exhibit tissue-specific expression. Mature erythrocytes express CD47 isoform 2 only, with membrane stability of this version dependent on inclusion within the band 3 macrocomplex,...

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Bibliographic Details
Main Authors: Kathryn E. Mordue, Bethan R. Hawley, Timothy J. Satchwell, Ashley M. Toye
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02356-1