Phenotypical Diversification of Early IFNα-Producing Human Plasmacytoid Dendritic Cells Using Droplet-Based Microfluidics

Phenotypical Diversification of Early IFNα-Producing Human Plasmacytoid Dendritic Cells Using Droplet-Based Microfluidics

Plasmacytoid dendritic cells (pDCs) are a rare type of highly versatile immune cells that besides their specialized function of massive type I interferon (IFN-I) production are able to exert cytotoxic effector functions. However, diversification upon toll like receptor (TLR)-induced activation leads...

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Bibliographic Details
Main Authors: Laura C. Van Eyndhoven, Eleni Chouri, Nikita Subedi, Jurjen Tel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
plasmacytoid dendritic cells
droplet-based microfluidics
diversification
heterogeneity
interferons
cytotoxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.672729/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.672729/full

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