HGF and IL-10 expressing ALB::GFP reporter cells generated from iPSCs show robust anti-fibrotic property in acute fibrotic liver model

HGF and IL-10 expressing ALB::GFP reporter cells generated from iPSCs show robust anti-fibrotic property in acute fibrotic liver model

Abstract Background Cell therapy using hepatocytes derived from stem cells has been regarded as a promising alternate to liver transplantation. However, the heterogeneity of these hepatocytes makes them unsuitable for therapeutic use. To overcome this limitation, we generated homogenous hepatocyte l...

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Bibliographic Details
Main Authors: Ja Sung Choi, In Sil Jeong, Young-Jin Park, Sung-Whan Kim
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Stem Cell Research & Therapy
Subjects:
Albumin
Cell therapy
Differentiation
Gene editing
Knock-in
Reporter system
Online Access:http://link.springer.com/article/10.1186/s13287-020-01745-0

Internet

http://link.springer.com/article/10.1186/s13287-020-01745-0

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