Disruption of Plasmodium falciparum histidine-rich protein 2 may affect haem metabolism in the blood stage

Disruption of Plasmodium falciparum histidine-rich protein 2 may affect haem metabolism in the blood stage

Abstract Background Haem is a key metabolic factor in the life cycle of the malaria parasite. In the blood stage, the parasite acquires host haemoglobin to generate amino acids for protein synthesis and the by-product haem for metabolic use. The malaria parasite can also synthesize haem de novo on i...

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Bibliographic Details
Main Authors: Yingchao Yang, Tongke Tang, Bo Feng, Shanshan Li, Nan Hou, Xiao Ma, Lubin Jiang, Xiaofang Xin, Qijun Chen
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Parasites & Vectors
Subjects:
HRP2
Haemoglobin
Haem metabolism
Haem biosynthesis
RNA-seq
Online Access:https://doi.org/10.1186/s13071-020-04460-0

Internet

https://doi.org/10.1186/s13071-020-04460-0

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