The Establishment of Esophageal Precancerous Lesion Model by Using p53 Conditional Knockout Mouse in Esophageal Epithelium

Understanding the molecular mechanisms of precancerous lesion of esophageal cancer is beneficial for early diagnosis and early treatment. The deletion of p53 gene is common in esophageal cancer, but its pathogenesis is still unclear. An animal model is urgently needed to study the mechanisms of esop...

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Bibliographic Details
Main Authors: Lili Zhu, Yanyan Xu, Xinhuan Chen, Jiace Qin, Tingting Niu, Yanyan Zhu, Yanan Jiang, Simin Zhao, Kangdong Liu, Jing Lu, Ge Jin, Junfen Ma, Ziming Dong, Jimin Zhao
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2020/4534289