Two-photon autofluorescence lifetime imaging of human skin papillary dermis in vivo: assessment of blood capillaries and structural proteins localization

Abstract The papillary dermis of human skin is responsible for its biomechanical properties and for supply of epidermis with chemicals. Dermis is mainly composed of structural protein molecules, including collagen and elastin, and contains blood capillaries. Connective tissue diseases, as well as ca...

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Bibliographic Details
Main Authors: Evgeny A. Shirshin, Yury I. Gurfinkel, Alexander V. Priezzhev, Victor V. Fadeev, Juergen Lademann, Maxim E. Darvin
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01238-w