Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice

Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice

The microbiota has been linked to the development of atherosclerosis, but the functional impact of these resident bacteria on the lesion size and cellular composition of atherosclerotic plaques in the aorta has never been experimentally addressed with the germ-free low-density lipoprotein receptor-d...

Full description

Bibliographic Details
Main Authors: Klytaimnistra Kiouptsi, Giulia Pontarollo, Hristo Todorov, Johannes Braun, Sven Jäckel, Thomas Koeck, Franziska Bayer, Cornelia Karwot, Angelica Karpi, Susanne Gerber, Yvonne Jansen, Philipp Wild, Wolfram Ruf, Andreas Daiber, Emiel Van Der Vorst, Christian Weber, Yvonne Döring, Christoph Reinhardt
Format: Article
Language:English
Published: Taylor & Francis Group 2020-11-01
Series:Gut Microbes
Subjects:
microbiota
germ-free
low-density lipoprotein receptor-deficient mouse
atherosclerosis
aortic root
aortic arch
macrophages
smooth muscle cells
inflammatory markers
age
lesion size
Online Access:http://dx.doi.org/10.1080/19490976.2020.1767463

Internet

http://dx.doi.org/10.1080/19490976.2020.1767463

Similar Items