Recent advances in SHH medulloblastoma progression: tumor suppressor mechanisms and the tumor microenvironment [version 1; peer review: 2 approved]

Medulloblastoma, the most common of the malignant pediatric brain tumors, is a group of four molecularly and clinically distinct cancers with different cells of origin. One of these medulloblastoma groups displays activation of Sonic hedgehog (SHH) signaling and originates from granule cell precurso...

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Bibliographic Details
Main Authors: Lukas Tamayo-Orrego, Frédéric Charron
Format: Article
Language:English
Published: F1000 Research Ltd 2019-10-01
Series:F1000Research
Online Access:https://f1000research.com/articles/8-1823/v1