Binding of Candida albicans to Human CEACAM1 and CEACAM6 Modulates the Inflammatory Response of Intestinal Epithelial Cells

Binding of Candida albicans to Human CEACAM1 and CEACAM6 Modulates the Inflammatory Response of Intestinal Epithelial Cells

Candida albicans colonizes human mucosa, including the gastrointestinal tract, as a commensal. In immunocompromised patients, C. albicans can breach the intestinal epithelial barrier and cause fatal invasive infections. Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1; CD66a), CEAC...

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Bibliographic Details
Main Authors: Esther Klaile, Mario M. Muller, Miriam R. Schafer, Ann-Katrin Clauder, Sabina Feer, Kerstin A. Heyl, Magdalena Stock, Tilman E. Klassert, Peter F. Zipfel, Bernhard B. Singer, Hortense Slevogt, Michael Lorenz
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/2/e02142-16

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http://mbio.asm.org/cgi/content/full/8/2/e02142-16

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