Heroin Inhibits HIV-Restriction miRNAs and Enhances HIV Infection of Macrophages

Heroin Inhibits HIV-Restriction miRNAs and Enhances HIV Infection of Macrophages

Although opioids have been extensively studied for their impact on the immune system, limited information is available about the specific actions of opioids on intracellular antiviral innate immunity against HIV infection. Thus, we investigated whether heroin, one of the most abused drugs, inhibits...

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Bibliographic Details
Main Authors: Xu eWang, Tong-Cui eMa, Jie-Liang eLi, Yu eZhou, Ellen B Geller, Martin W Adler, Jinsong ePeng, Dun-Jin eZhou, Wang eZhou, Wen-Zhe eHo
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Microbiology
Subjects:
Heroin
HIV
macrophage
miRNAs
IFN-alpha
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01230/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01230/full

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