Elevated MiR-222-3p promotes proliferation and invasion of endometrial carcinoma via targeting ERα.

MicroRNAs play key roles in tumor proliferation and invasion. Here we show distinct expression of miR-222-3p between ERα-positive and ERα-negative endometrial carcinoma (EC) cell lines and primary tumors, and investigation of its relationship with ERα and other clinical parameters. In vitro, the fun...

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Bibliographic Details
Main Authors: Binya Liu, Qi Che, Haifeng Qiu, Wei Bao, Xiaoyue Chen, Wen Lu, Bilan Li, Xiaoping Wan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3909214?pdf=render