Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors.

Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors.

<h4>Background</h4>Genome-wide association studies have identified susceptibility genes for development of type 2 diabetes. We aimed to examine whether a subset of these (comprising FTO, IDE, KCNJ11, PPARG and TCF7L2) were transcriptionally restricted to or enriched in human beta cells b...

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Bibliographic Details
Main Authors: Clare L Kirkpatrick, Piero Marchetti, Francesco Purrello, Salvatore Piro, Marco Bugliani, Domenico Bosco, Eelco J P de Koning, Marten A Engelse, Julie Kerr-Conte, François Pattou, Claes B Wollheim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20548773/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20548773/?tool=EBI

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