Preparation and Evaluation of the Fully Humanized Monoclonal Antibody GD-mAb Against Respiratory Syncytial Virus

Preparation and Evaluation of the Fully Humanized Monoclonal Antibody GD-mAb Against Respiratory Syncytial Virus

Respiratory syncytial virus (RSV) is the major cause of pulmonary and bronchial inflammation in infants, young children, and immunocompromised adults, but therapeutic options to control RSV are limited. In the present study a single chain antibody against RSV (GD-scFv) was screened using phage displ...

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Bibliographic Details
Main Authors: Puyuan Tian, Yuqing Wang, Hui Liu, Yulu Yang, Xiaoli Wu, Hua Wei, Tingtao Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
respiratory syncytial virus (RSV)
phage display technology
monoclonal antibody
inflammation
signal pathway
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00275/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00275/full

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