Activation of р-450-depended monooxygenases changing immunotoxicity of phosphoroorganic compounds due to their metabolism character

It was established that the application of the monooxygenase system inductors (MSI) of phenobarbital and benzonal up to acute poisoning of animals by trichlorfom in a dose of 1,0 LD50, metabolized in the organism till production of compounds with higher toxicity caused its immunotoxic properties inc...

Full description

Bibliographic Details
Main Authors: P.F. Zabrodsky, V.F. Kirichuk, V.G. Lim, I.Kh. Yafarova
Format: Article
Language:Russian
Published: Saratov State Medical University 2010-03-01
Series:Саратовский научно-медицинский журнал
Subjects:
Online Access:http://www.ssmj.ru/system/files/201001_046_048.pdf