Assessment of drug-induced proarrhythmias due to pilsicainide in patients with atrial tachyarrhythmias

Assessment of drug-induced proarrhythmias due to pilsicainide in patients with atrial tachyarrhythmias

Background: Pilsicainide, a pure Na+ channel blocker, is a popular antiarrhythmic drug for the management of atrial tachyarrhythmias (AT), in Japan. However, serious drug-induced proarrhythmias (DIPs) may unexpectedly occur. We assessed the clinical background of AT patients presenting with DIPs cau...

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Bibliographic Details
Main Authors: Hideki Koike, MD, Tadashi Fujino, MD, PhD, Makiko Koike, MD, Shintaro Yao, MD, Masaya Shinohara, MD, Ken Kitahara, MD, PhD, Toshio Kinoshita, MD, PhD, Hitomi Yuzawa, MD, Takeya Suzuki, MD, PhD, Hideyuki Sato, MD, Shunji Fukunaga, MD, Kenzaburo Kobayashi, MD, PhD, Takanori Ikeda, MD, PhD, FJCC
Format: Article
Language:English
Published: Wiley 2016-12-01
Series:Journal of Arrhythmia
Subjects:
Pilsicainide
Proarrhythmia
Renal dysfunction
QRS interval
QTc interval
Online Access:http://www.sciencedirect.com/science/article/pii/S1880427616300266

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http://www.sciencedirect.com/science/article/pii/S1880427616300266

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