Esculin protects against methionine choline-deficient diet-induced non-alcoholic steatohepatitis by regulating the Sirt1/NF-B p65 pathway

Esculin protects against methionine choline-deficient diet-induced non-alcoholic steatohepatitis by regulating the Sirt1/NF-B p65 pathway

Context Esculin, an active coumarin compound, has been demonstrated to exert anti-inflammatory effects. However, its potential role in non-alcoholic steatohepatitis (NASH) remains unclear. Objective This study explored the hepatoprotective effect and the molecular mechanism of esculin in methionine...

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Bibliographic Details
Main Authors: Xi-Ding Yang, Zhuo Chen, Ling Ye, Jing Chen, Yong-Yu Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Pharmaceutical Biology
Subjects:
inflammatory cytokine
acetylation of nf-κb p65
fibrosis
Online Access:http://dx.doi.org/10.1080/13880209.2021.1945112

Internet

http://dx.doi.org/10.1080/13880209.2021.1945112

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