Oncolytic Herpes Virus rRp450 Shows Efficacy in Orthotopic Xenograft Group 3/4 Medulloblastomas and Atypical Teratoid/Rhabdoid Tumors

Oncolytic Herpes Virus rRp450 Shows Efficacy in Orthotopic Xenograft Group 3/4 Medulloblastomas and Atypical Teratoid/Rhabdoid Tumors

Pediatric brain tumors including medulloblastoma and atypical teratoid/rhabdoid tumor are associated with significant mortality and treatment-associated morbidity. While medulloblastoma tumors within molecular subgroups 3 and 4 have a propensity to metastasize, atypical teratoid/rhabdoid tumors freq...

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Bibliographic Details
Main Authors: Adam W. Studebaker, Brian J. Hutzen, Christopher R. Pierson, Kellie B. Haworth, Timothy P. Cripe, Eric M. Jackson, Jeffrey R. Leonard
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Molecular Therapy: Oncolytics
Subjects:
oncolytic virus
brain tumors
medulloblastoma
pediatric oncology
herpes simplex virus
atypical teratoid rhabdoid tumor
cyclophosphamide
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770517300244

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http://www.sciencedirect.com/science/article/pii/S2372770517300244

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