Thymic Epithelial Cell Development and Its Dysfunction in Human Diseases

Thymic epithelial cells (TECs) are the key components in thymic microenvironment for T cells development. TECs, composed of cortical and medullary TECs, are derived from a common bipotent progenitor and undergo a stepwise development controlled by multiple levels of signals to be functionally mature...

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Bibliographic Details
Main Authors: Lina Sun, Hongran Li, Haiying Luo, Yong Zhao
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/206929