Decreased phenotypic susceptibility to etravirine in patients with predicted genotypic sensitivity.

BACKGROUND: A sensitive, phenotypic reverse transcriptase (RT)-based drug susceptibility assay for the detection of etravirine (ETR) resistance in patient isolates was developed and compared with the results from direct sequencing and ultra-deep pyrosequencing (UDPS). METHODS: Samples were obtained...

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Bibliographic Details
Main Authors: Eva Agneskog, Piotr Nowak, Catharina Maijgren Steffensson, Maria Casadellà, Marc Noguera-Julian, Roger Paredes, Clas F R Källander, Anders Sönnerborg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4084891?pdf=render