Evaluation of aflibercept and ziv-aflibercept binding affinity to vascular endothelial growth factor, stability and sterility after compounding

Abstract Purpose To investigate the binding affinity, stability, and sterility of aflibercept and ziv-aflibercept to vascular endothelial growth factor (Holash et al. in Proc Natl Acad Sci USA 99(17):11393–11398, 2002. https://doi.org/10.1073/pnas.172398299) after compounding and storage for up to 2...

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Main Authors: Julia de Lima Farah, Ronaldo Sano, Ieda Maria Longo Maugéri, Daniela Teixeira, Mayari Eika Ishimura, Gabriela Martins, Lycia M. J. Mimica, Cely Barreto da Silva, Carsten H. Meyer, João Rafael de Oliveira Dias, Gabriel Costa de Andrade, Michel Eid Farah
Format: Article
Language:English
Published: BMC 2018-10-01
Series:International Journal of Retina and Vitreous
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40942-018-0143-x