Markers of sulfadoxine–pyrimethamine resistance in Eastern Democratic Republic of Congo; implications for malaria chemoprevention

Markers of sulfadoxine–pyrimethamine resistance in Eastern Democratic Republic of Congo; implications for malaria chemoprevention

Abstract Background Sulfadoxine–pyrimethamine (SP) is a cornerstone of malaria chemoprophylaxis and is considered for programmes in the Democratic Republic of Congo (DRC). However, SP efficacy is threatened by drug resistance, that is conferred by mutations in the dhfr and dhps genes. The World Heal...

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Bibliographic Details
Main Authors: Marit van Lenthe, Renske van der Meulen, Maryvonne Lassovski, Adelaide Ouabo, Edwige Bakula, Colette Badio, Deogratias Cibenda, Lucy Okell, Erwan Piriou, Lynn Grignard, Kjerstin Lanke, Bhargavi Rao, Teun Bousema, Cally Roper
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Malaria Journal
Subjects:
Malaria
DRC
Sulfadoxine–pyrimethamine (SP)
Chemoprophylaxis
dhps
dhfr
Online Access:https://doi.org/10.1186/s12936-019-3057-7

Internet

https://doi.org/10.1186/s12936-019-3057-7

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