Association between response to albendazole treatment and β-tubulin genotype frequencies in soil-transmitted helminths.

Albendazole (ABZ), a benzimidazole (BZ) anthelmintic (AH), is commonly used for treatment of soil-transmitted helminths (STHs). Its regular use increases the possibility that BZ resistance may develop, which, in veterinary nematodes is caused by single nucleotide polymorphisms (SNPs) in the β-tubuli...

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Main Authors: Aïssatou Diawara, Carli M Halpenny, Thomas S Churcher, Charles Mwandawiro, Jimmy Kihara, Ray M Kaplan, Thomas G Streit, Youssef Idaghdour, Marilyn E Scott, Maria-Gloria Basáñez, Roger K Prichard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3667785?pdf=render