Autophagy facilitates type I collagen synthesis in periodontal ligament cells
Abstract Autophagy is a lysosomal protein degradation system in which the cell self-digests its intracellular protein components and organelles. Defects in autophagy contribute to the pathogenesis of age-related chronic diseases, such as myocardial infarction and rheumatoid arthritis, through defect...
Main Authors: | Tomomi Nakamura, Motozo Yamashita, Kuniko Ikegami, Mio Suzuki, Manabu Yanagita, Jirouta Kitagaki, Masahiro Kitamura, Shinya Murakami |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-80275-4 |
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