MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord

MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord

In the spinal cord, someHox genes are transcribed in progenitors while their proteins are only detected in differentiating postmitotic motor neurons. Here, the authors show that miRNAs (specifically mir-27) regulate post-transcriptional Hoxa5 expression in motor neurons.

Bibliographic Details
Main Authors: Chung-Jung Li, Tian Hong, Ying-Tsen Tung, Ya-Ping Yen, Ho-Chiang Hsu, Ya-Lin Lu, Mien Chang, Qing Nie, Jun-An Chen
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14685

Internet

https://doi.org/10.1038/ncomms14685

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