Extracellular vesicles as modifiers of antibody‐drug conjugate efficacy

Abstract Antibody‐drug conjugates (ADCs) are a new class of anti‐cancer drugs that consist of a monoclonal antibody, a highly potent small‐molecule cytotoxic drug, and a chemical linker between the two. ADCs can selectively deliver cytotoxic drugs to cancer cells leading to a reduced systemic exposu...

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Bibliographic Details
Main Authors: Mark Barok, Maija Puhka, Narjes Yazdi, Heikki Joensuu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-02-01
Series:Journal of Extracellular Vesicles
Subjects:
Online Access:https://doi.org/10.1002/jev2.12070