Exploiting Protected Maleimides to Modify Oligonucleotides, Peptides and Peptide Nucleic Acids

This manuscript reviews the possibilities offered by 2,5-dimethylfuran-protected maleimides. Suitably derivatized building blocks incorporating the exo Diels-Alder cycloadduct can be introduced at any position of oligonucleotides, peptide nucleic acids, peptides and peptoids, making use of standard...

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Bibliographic Details
Main Authors: Clément Paris, Omar Brun, Enrique Pedroso, Anna Grandas
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/4/6389