Transient nature of long-term nonprogression and broad virus-specific proliferative T-cell responses with sustained thymic output in HIV-1 controllers.

Transient nature of long-term nonprogression and broad virus-specific proliferative T-cell responses with sustained thymic output in HIV-1 controllers.

HIV-1(+) individuals who, without therapy, conserve cellular anti-HIV-1 responses, present with high, stable CD4(+) T-cell numbers, and control viral replication, facilitate analysis of atypical viro-immunopathology. In the absence of universal definition, immune function in such HIV controllers rem...

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Bibliographic Details
Main Authors: Samantha J Westrop, Nadeem A Qazi, Jeffrey Pido-Lopez, Mark R Nelson, Brian Gazzard, Frances M Gotch, Nesrina Imami
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2677159?pdf=render

Internet

http://europepmc.org/articles/PMC2677159?pdf=render

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