Role of Stat3 Signaling in Control of EMT of Tubular Epithelial Cells During Renal Fibrosis

Role of Stat3 Signaling in Control of EMT of Tubular Epithelial Cells During Renal Fibrosis

Background/Aims: Transforming growth factor β 1 (TGFβ1) plays a critical role in the epithelial-to-mesenchymal transition (EMT) of renal tubular epithelial cells (TECs) during renal injury, a major cause of acute renal failure, renal fibrosis and obstructive nephropathy. However, the underlying mole...

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Bibliographic Details
Main Authors: Jingsong Liu, Ying Zhong, Guoyong Liu, Xiaobai Zhang, Bofei Xiao, Shang Huang, Hong Liu, Liyu He
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Stat3
Renal fibrosis
TGFβ1
Epithelial-to-mesenchymal transition
Online Access:http://www.karger.com/Article/FullText/480216

Internet

http://www.karger.com/Article/FullText/480216

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