Cytotoxic Potential of the Novel Horseshoe Crab Peptide Polyphemusin III

Cytotoxic Potential of the Novel Horseshoe Crab Peptide Polyphemusin III

Biological activity of the new antimicrobial peptide polyphemusin III from the horseshoe crab <i>Limulus polyphemus</i> was examined against bacterial strains and human cancer, transformed, and normal cell cultures. Polyphemusin III has the amino acid sequence RRGCFRVCYRGFCFQRCR and is h...

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Bibliographic Details
Main Authors: Mariana B. Marggraf, Pavel V. Panteleev, Anna A. Emelianova, Maxim I. Sorokin, Ilia A. Bolosov, Anton A. Buzdin, Denis V. Kuzmin, Tatiana V. Ovchinnikova
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Marine Drugs
Subjects:
antimicrobial peptide
cytotoxicity
β-hairpin
polyphemusins
tachyplesins
cell death
signaling pathways
Online Access:https://www.mdpi.com/1660-3397/16/12/466

Internet

https://www.mdpi.com/1660-3397/16/12/466

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