Sodium stibogluconate (SSG) & paromomycin combination compared to SSG for visceral leishmaniasis in East Africa: a randomised controlled trial.

Alternative treatments for visceral leishmaniasis (VL) are required in East Africa. Paromomycin sulphate (PM) has been shown to be efficacious for VL treatment in India.A multi-centre randomized-controlled trial (RCT) to compare efficacy and safety of PM (20 mg/kg/day for 21 days) and PM plus sodium...

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Main Authors: Ahmed Musa, Eltahir Khalil, Asrat Hailu, Joseph Olobo, Manica Balasegaram, Raymond Omollo, Tansy Edwards, Juma Rashid, Jane Mbui, Brima Musa, Abuzaid Abdalla Abuzaid, Osama Ahmed, Ahmed Fadlalla, Ahmed El-Hassan, Marius Mueller, Geoffrey Mucee, Simon Njoroge, Veronica Manduku, Geoffrey Mutuma, Lilian Apadet, Hudson Lodenyo, Dedan Mutea, George Kirigi, Sisay Yifru, Getahun Mengistu, Zewdu Hurissa, Workagegnehu Hailu, Teklu Weldegebreal, Hailemariam Tafes, Yalemtsehay Mekonnen, Eyasu Makonnen, Serah Ndegwa, Patrick Sagaki, Robert Kimutai, Josephine Kesusu, Rhoda Owiti, Sally Ellis, Monique Wasunna
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3378617?pdf=render