The Combination of Propofol and Ketamine Does Not Enhance Clinical Responses to Electroconvulsive Therapy in Major Depression—The Results From the KEOpS Study

ObjectiveWe investigated the clinical effects of the combination of ketamine and propofol as anesthetic agents during electroconvulsive therapy (ECT) in patients with uni- or bipolar major depressive episodes. We hypothesized that ketamine may confer short- and long- term advantages in improving dep...

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Bibliographic Details
Main Authors: Jerome Brunelin, Sylvain Iceta, Marion Plaze, Raphaël Gaillard, Louis Simon, Marie-Françoise Suaud-Chagny, Filipe Galvao, Emmanuel Poulet
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.562137/full