Emergence of a Broad Repertoire of GAD65-Specific T-Cells in Type 1 Diabetes Patients with Graft Dysfunction after Allogeneic Islet Transplantation

Emergence of a Broad Repertoire of GAD65-Specific T-Cells in Type 1 Diabetes Patients with Graft Dysfunction after Allogeneic Islet Transplantation

Islet transplantation is one of the most promising therapies for type 1 diabetes (T1D). A major issue in islet transplantation is the loss of graft function at late phase. Several studies suggested the involvement of islet-specific T-cells in such islet graft dysfunction. In this study, we investiga...

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Bibliographic Details
Main Authors: Daisuke Chujo, Emile Foucat, Morihito Takita, Takeshi Itoh, Koji Sugimoto, Masayuki Shimoda, Kunimasa Yagi, Masakazu Yamagishi, Yoshiko Tamura, Liping Yu, Bashoo Naziruddin, Marlon F. Levy, Hideki Ueno M.D., Ph.D., Shinichi Matsumoto
Format: Article
Language:English
Published: SAGE Publishing 2012-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X654993

Internet

https://doi.org/10.3727/096368912X654993

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