Proteomic analysis of ovarian cancer cells reveals dynamic processes of protein secretion and shedding of extra-cellular domains.

Proteomic analysis of ovarian cancer cells reveals dynamic processes of protein secretion and shedding of extra-cellular domains.

BACKGROUND: Elucidation of the repertoire of secreted and cell surface proteins of tumor cells is relevant to molecular diagnostics, tumor imaging and targeted therapies. We have characterized the cell surface proteome and the proteins released into the extra-cellular milieu of three ovarian cancer...

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Bibliographic Details
Main Authors: Vitor M Faça, Aviva P Ventura, Mathew P Fitzgibbon, Sandra R Pereira-Faça, Sharon J Pitteri, Ann E Green, Renee C Ireton, Qing Zhang, Hong Wang, Kathy C O'Briant, Charles W Drescher, Michèl Schummer, Martin W McIntosh, Beatrice S Knudsen, Samir M Hanash
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2409963?pdf=render

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http://europepmc.org/articles/PMC2409963?pdf=render

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