The efficacy of cetuximab in a tissue-engineered three-dimensional in vitro model of colorectal cancer
The preclinical development process of chemotherapeutic drugs is often carried out in two-dimensional monolayer cultures. However, a considerable amount of evidence demonstrates that two-dimensional cell culture does not accurately reflect the three-dimensional in vivo tumour microenvironment, speci...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2014-07-01
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Series: | Journal of Tissue Engineering |
Online Access: | https://doi.org/10.1177/2041731414544183 |