A SERM increasing the expression of the osteoblastogenesis and mineralization-related proteins and improving quality of bone tissue in an experimental model of osteoporosis

A SERM increasing the expression of the osteoblastogenesis and mineralization-related proteins and improving quality of bone tissue in an experimental model of osteoporosis

Abstract Raloxifene is an antiresorptive drug, selective estrogen receptor modulator (SERM) used in the treatment of osteoporosis. Objective To evaluate proteins related to bone repair at the peri-implant bone in a rat model of osteoporosis treated with raloxifene. Material and Methods 72 rats wer...

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Bibliographic Details
Main Authors: Fernanda Costa Yogui, Gustavo Antonio Correa Momesso, Leonardo Perez Faverani, Tarik Ocon Braga Polo, Gabriel Ramalho-Ferreira, Jaqueline Suemi Hassumi, Ana Cláudia Rossi, Alexandre Rodrigues Freire, Felippe Bevilacqua Prado, Roberta Okamoto
Format: Article
Language:English
Published: University of São Paulo 2018-05-01
Series:Journal of Applied Oral Science
Subjects:
Raloxifene
Immunohistochemistry
Osteoporosis
Dental implants
WNT signaling
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572018000100447&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572018000100447&lng=en&tlng=en

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