RSAT variation-tools: An accessible and flexible framework to predict the impact of regulatory variants on transcription factor binding

RSAT variation-tools: An accessible and flexible framework to predict the impact of regulatory variants on transcription factor binding

Gene regulatory regions contain short and degenerated DNA binding sites recognized by transcription factors (TFBS). When TFBS harbor SNPs, the DNA binding site may be affected, thereby altering the transcriptional regulation of the target genes. Such regulatory SNPs have been implicated as causal va...

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Bibliographic Details
Main Authors: Walter Santana-Garcia, Maria Rocha-Acevedo, Lucia Ramirez-Navarro, Yvon Mbouamboua, Denis Thieffry, Morgane Thomas-Chollier, Bruno Contreras-Moreira, Jacques van Helden, Alejandra Medina-Rivera
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Computational and Structural Biotechnology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037019301898

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http://www.sciencedirect.com/science/article/pii/S2001037019301898

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