Metabolic Flexibility and Innate Immunity in Renal Ischemia Reperfusion Injury: The Fine Balance Between Adaptive Repair and Tissue Degeneration

Metabolic Flexibility and Innate Immunity in Renal Ischemia Reperfusion Injury: The Fine Balance Between Adaptive Repair and Tissue Degeneration

Renal ischemia reperfusion injury (IRI), a common event after renal transplantation, causes acute kidney injury (AKI), increases the risk of delayed graft function (DGF), primes the donor kidney for rejection, and contributes to the long-term risk of graft loss. In the last decade, epidemiological s...

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Bibliographic Details
Main Authors: Alessandra Tammaro, Jesper Kers, Angelique M. L. Scantlebery, Sandrine Florquin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
kidney transplantation
tubular repair
innate immunity
cell death
mitochondria
senescence
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01346/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01346/full

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