Protective activation of the endocannabinoid system during ischemia in dopamine neurons

Protective activation of the endocannabinoid system during ischemia in dopamine neurons

Endocannabinoids act as neuroprotective molecules promptly released in response to pathological stimuli. Hence, they may represent one component of protection and/or repair mechanisms mobilized by dopamine (DA) neurons under ischemia. Here, we show that the endocannabinoid 2-arachidonoyl-glycerol (2...

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Bibliographic Details
Main Authors: Miriam Melis, Giuliano Pillolla, Tiziana Bisogno, Alberto Minassi, Stefania Petrosino, Simona Perra, Anna Lisa Muntoni, Beat Lutz, Gian Luigi Gessa, Giovanni Marsicano, Vincenzo Di Marzo, Marco Pistis
Format: Article
Language:English
Published: Elsevier 2006-10-01
Series:Neurobiology of Disease
Subjects:
CB1
Dopamine
Endocannabinoid
Ischemia
Midbrain
Neuroprotection
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106000982

Internet

http://www.sciencedirect.com/science/article/pii/S0969996106000982

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