Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures

The correlation between brain structural changes in major depressive disorder (MDD) and gene expression is unclear. Here, the authors explore the correlation between cell type-specific gene expression changes and cortical structural difference in individuals with major depressive disorder.

Bibliographic Details
Main Authors: Jiao Li, Jakob Seidlitz, John Suckling, Feiyang Fan, Gong-Jun Ji, Yao Meng, Siqi Yang, Kai Wang, Jiang Qiu, Huafu Chen, Wei Liao
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21943-5